棒酸增强阿洛西林对脆弱拟杆菌的体外活性。
Augmentation of the in vitro activity of azlocillin against Bacteroides fragilis by clavulanic acid.
作者信息
Bansal M B, Chuah S K, Thadepalli H
出版信息
Antimicrob Agents Chemother. 1984 Oct;26(4):606-7. doi: 10.1128/AAC.26.4.606.
Abstract
Azlocillin was active against 90% of 154 strains of Bacteroides fragilis at a concentration of 64 micrograms/ml. Twenty-eight strains of B. fragilis with an azlocillin MIC of greater than or equal to 8 micrograms/ml were retested with a combination of azlocillin plus clavulanic acid. Of these strains, 71% showed a 4- to 32-fold decrease in the MIC of azlocillin plus clavulanic acid.
摘要
阿洛西林对154株脆弱拟杆菌中的90%在浓度为64微克/毫升时具有活性。对28株阿洛西林最低抑菌浓度（MIC）大于或等于8微克/毫升的脆弱拟杆菌菌株，用阿洛西林加克拉维酸联合进行重新检测。在这些菌株中，71%显示阿洛西林加克拉维酸的MIC下降了4至32倍。
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