克拉维酸对十种β-内酰胺类药物针对脆弱拟杆菌群成员活性的影响。
Effect of clavulanic acid on the activities of ten beta-lactam agents against members of the Bacteroides fragilis group.
作者信息
Lamothe F, Auger F, Lacroix J M
出版信息
Antimicrob Agents Chemother. 1984 May;25(5):662-5. doi: 10.1128/AAC.25.5.662.
Abstract
Clavulanic acid reduced the MICs of amoxicillin, carbencillin , cefamandole, cefotaxime, ceftazidime, ceftizoxime, cephalothin, and penicillin G, but not of cefoxitin or moxalactam, against 77 isolates of the Bacteroides fragilis group, all rapidly beta-lactamase positive by the nitrocefin slide test. It had no effect on the susceptibilities of eight Bacteroides distasonis strains that were slowly beta-lactamase positive (18 h of incubation).
摘要
棒酸降低了阿莫西林、羧苄西林、头孢孟多、头孢噻肟、头孢他啶、头孢唑肟、头孢噻吩和青霉素G对77株脆弱拟杆菌属菌株的最低抑菌浓度（MIC），但对头孢西丁或莫拉维酸的MIC没有影响，所有菌株通过硝基头孢菌素纸片试验均快速产β-内酰胺酶。它对8株缓慢产β-内酰胺酶（培养18小时）的狄氏拟杆菌菌株的敏感性没有影响。
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本文引用的文献
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