Korth H, Müller I, Erckenbrecht J F, Wienbeck M
Hepatogastroenterology. 1984 Dec;31(6):282-4.
Intestinal transit is an important indicator of small-bowel function. This study served to investigate oro-cecal and duodeno-cecal transit times of different carbohydrate test meals and to evaluate intra- and interindividual variability of the breath hydrogen test. Breath hydrogen was analysed by an electrochemical cell in 25 healthy volunteers. Oro-cecal transit time of lactulose was much shorter than that of a standardized normal test meal. Duodeno-cecal transit was approximately one hour shorter than oro-cecal transit. Considerable intra- and interindividual differences were observed. It is concluded that results of lactulose test meals do not permit conclusions as to the physiological situation. Large intra- and interindividual variability of transit times must be taken into account in any study using the breath hydrogen test.
肠道转运是小肠功能的一项重要指标。本研究旨在调查不同碳水化合物测试餐的口盲肠和十二指肠盲肠转运时间，并评估呼气氢试验的个体内和个体间变异性。通过电化学电池对25名健康志愿者的呼气氢进行了分析。乳果糖的口盲肠转运时间比标准化正常测试餐的口盲肠转运时间短得多。十二指肠盲肠转运时间比口盲肠转运时间大约短一小时。观察到个体内和个体间存在相当大的差异。得出的结论是，乳果糖测试餐的结果不能得出关于生理状况的结论。在任何使用呼气氢试验的研究中，都必须考虑转运时间的个体内和个体间的巨大变异性。
