Hüppe D, Tönissen R, Hofius M, Kuntz H D, May B
Berufsgenossenschaftliche Krankenanstalten Bermannsheil Bochum, Universitätsklinik.
Z Gastroenterol. 1989 Oct;27(10):624-8.
In a clinical study (1.1.1986-28.2.1988) the oro-cecal transit time of lactulose was studied in 45 patients with liver cirrhosis of different etiologies by hydrogen breath test. The results were compared to the transit time of 16 healthy volunteers. The oro-cecal transit time of patients with alcoholic cirrhosis (means = 154 +/- 29 min.) was significantly increased (P less than or equal to 0.001) while non alcoholic cirrhosis (means = 99 +/- 34 min.) did not differ from the control group (means = 98 +/- 16 min.) As an explanation of the increased oro-cecal transit time an alcoholic autonomic neuropathy (- greater than n. vagus) is discussed.
在一项临床研究（1986年1月1日至1988年2月28日）中，通过氢呼气试验对45例不同病因的肝硬化患者进行了乳果糖的口盲肠转运时间研究。将结果与16名健康志愿者的转运时间进行了比较。酒精性肝硬化患者的口盲肠转运时间（平均值=154±29分钟）显著延长（P≤0.001），而非酒精性肝硬化患者（平均值=99±34分钟）与对照组（平均值=98±16分钟）无差异。作为口盲肠转运时间延长的一种解释，讨论了酒精性自主神经病变（→迷走神经）。
