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Mean residence time in peripheral tissue: a linear disposition parameter useful for evaluating a drug's tissue distribution.

作者信息

Veng-Pedersen P, Gillespie W

出版信息

J Pharmacokinet Biopharm. 1984 Oct;12(5):535-43. doi: 10.1007/BF01060131.

DOI:10.1007/BF01060131
PMID:6520747
Abstract
摘要

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The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time.统计矩理论在体内溶出时间和吸收时间评估中的应用。
J Pharmacokinet Biopharm. 1980 Oct;8(5):509-34. doi: 10.1007/BF01059549.
2
Noncompartmental determination of the steady-state volume of distribution for any mode of administration.非房室模型法测定任何给药方式下的稳态分布容积。
J Pharm Sci. 1982 Mar;71(3):372-3. doi: 10.1002/jps.2600710332.
3
Acceleration of the body clearance of phenobarbital by oral activated charcoal.
局部应用后水杨酸的皮肤及皮下组织药代动力学
J Pharmacokinet Biopharm. 1993 Aug;21(4):337-73. doi: 10.1007/BF01061687.
4
A technique for calculating the mean time for equilibration of drug distribution using minimal structural assumptions.一种使用最少结构假设来计算药物分布平衡平均时间的技术。
J Pharmacokinet Biopharm. 1994 Apr;22(2):157-64. doi: 10.1007/BF02353541.
5
Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. II. Clearance concepts applied to the evaluation of distribution kinetics.线性及某些非线性药物处置的模型无关消除/分布函数分解的定理及推论。II. 应用于分布动力学评估的清除概念。
J Pharmacokinet Biopharm. 1985 Aug;13(4):441-51. doi: 10.1007/BF01061479.
6
The determination of mean residence time using statistical moments: it is correct.
J Pharmacokinet Biopharm. 1985 Oct;13(5):549-54. doi: 10.1007/BF01059336.
7
Mean residence time in peripheral tissue.
J Pharmacokinet Biopharm. 1987 Aug;15(4):439-50. doi: 10.1007/BF01066523.
8
Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. III. Peripheral bioavailability and distribution time concepts applied to the evaluation of distribution kinetics.线性及某些非线性药物处置的模型无关消除/分布函数分解的定理与推论。III. 应用于分布动力学评估的外周生物利用度和分布时间概念
J Pharmacokinet Biopharm. 1987 Jun;15(3):281-304. doi: 10.1007/BF01066323.
9
General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment.具有从任何隔室消除的线性乳突模型中平均停留时间、清除率和容积参数的一般处理。
J Pharmacokinet Biopharm. 1988 Oct;16(5):475-92. doi: 10.1007/BF01062381.
10
Linear and nonlinear system approaches in pharmacokinetics: how much do they have to offer? I. General considerations.
J Pharmacokinet Biopharm. 1988 Aug;16(4):413-72. doi: 10.1007/BF01062554.
口服活性炭加速苯巴比妥的体内清除率。
N Engl J Med. 1982 Sep 9;307(11):642-4. doi: 10.1056/NEJM198209093071102.
4
Computation of model-independent pharmacokinetic parameters during multiple dosing.
J Pharm Sci. 1984 Apr;73(4):570-1. doi: 10.1002/jps.2600730436.
5
Pharmacokinetics of intravenous theophylline.静脉注射氨茶碱的药代动力学
Clin Pharmacol Ther. 1973 Jul-Aug;14(4):509-13. doi: 10.1002/cpt1973144part1509.
6
The pharmacokinetics of propylthiouracil.丙硫氧嘧啶的药代动力学。
Acta Pharmacol Toxicol (Copenh). 1974 Nov;35(5):361-9. doi: 10.1111/j.1600-0773.1974.tb00756.x.
7
Pharmacokinetics of digoxin in normal subjects after intravenous bolus and infusion doses.
J Pharmacokinet Biopharm. 1975 Jun;3(3):181-92. doi: 10.1007/BF01067907.
8
Pharmocokinetics of hexobarbital in man after intravenous infusion.
J Pharmacokinet Biopharm. 1975 Feb;3(1):1-11. doi: 10.1007/BF01066591.
9
Statistical moments in pharmacokinetics.药代动力学中的统计矩
J Pharmacokinet Biopharm. 1978 Dec;6(6):547-58. doi: 10.1007/BF01062109.
10
Theory of the mean absorption time, an adjunct to conventional bioavailability studies.平均吸收时间理论，传统生物利用度研究的辅助手段。
J Pharm Pharmacol. 1978 Aug;30(8):476-8. doi: 10.1111/j.2042-7158.1978.tb13296.x.