Keyzer J J, van Saene H K, van den Berg G A, Wolthers B G
Agents Actions. 1984 Oct;15(3-4):238-41. doi: 10.1007/BF01972355.
Urinary excretions of histamine, N tau-methylhistamine and N tau-methylimidazoleacetic acid have been determined for 8 healthy volunteers during 14 consecutive days. Selective decontamination of the digestive tract was performed from day 3 to day 6, followed by total decontamination from day 7 to day 10. Urinary excretions of N tau-methylhistamine and N tau-methylimidazoleacetic acid decreased to a small though significant degree (about 15-20%) after total decontamination, suggesting a histamine production by anaerobic bacteria. Cadaverine decreased for about 70% under both selective and total decontamination, suggesting that this amine in human urine mainly originates from aerobic bacteria in the intestinal tract.
对8名健康志愿者连续14天的尿液中组胺、N-τ-甲基组胺和N-τ-甲基咪唑乙酸的排泄情况进行了测定。从第3天至第6天对消化道进行选择性去污，随后从第7天至第10天进行全面去污。全面去污后，N-τ-甲基组胺和N-τ-甲基咪唑乙酸的尿液排泄量虽有小幅但显著的下降（约15%-20%），这表明厌氧菌可产生组胺。在选择性去污和全面去污两种情况下，尸胺均下降了约70%，这表明人尿液中的这种胺主要源自肠道中的需氧菌。
