Yazici H, Tüzün Y, Pazarli H, Yurdakul S, Ozyazgan Y, Ozdoğan H, Serdaroğlu S, Ersanli M, Ulkü B Y, Müftüoğlu A U
Ann Rheum Dis. 1984 Dec;43(6):783-9. doi: 10.1136/ard.43.6.783.
Eye disease, arthritis, folliculitis, and thrombophlebitis were more common among males, and erythema nodosum among females, in 297 patients with Behćet syndrome (BS) at their first visit despite an identical disease duration. Younger males and females (age of onset 24 years or less) had a higher prevalence of eye disease and total clinical activity than did the older patients (age of onset 25 years or more). Among the 51 patients followed up for 52 months (SD 7 months) the total clinical activity became significantly less (p less than 0.05) in the whole group at the end of this period. This was particularly true for older females. While male sex and a younger age of onset are associated with more severe disease in BS, overall, the syndrome ran an improving or stable course over 4 1/2 years.
在297例初诊的白塞病（BS）患者中，尽管病程相同，但眼病、关节炎、毛囊炎和血栓性静脉炎在男性中更为常见，结节性红斑在女性中更为常见。年轻男性和女性（发病年龄24岁及以下）比老年患者（发病年龄25岁及以上）眼病患病率和总体临床活动度更高。在随访52个月（标准差7个月）的51例患者中，在此期间结束时，整个组的总体临床活动度显著降低（p<0.05）。老年女性尤其如此。虽然男性性别和较年轻的发病年龄与白塞病中更严重的疾病相关，但总体而言，该综合征在4年半的时间里病情呈改善或稳定趋势。
