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体外导管定植模型及其与临床导管感染的关系。

A model of catheter colonisation in vitro and its relationship to clinical catheter infections.

作者信息

Bayston R

出版信息

J Infect. 1984 Nov;9(3):271-6. doi: 10.1016/s0163-4453(84)90596-6.

DOI:10.1016/s0163-4453(84)90596-6
PMID:6527042
Abstract

A laboratory model for colonisation of silicone-rubber catheters by staphylococci is described. The criteria for true colonisation that involves adhesion of the organisms to the luminal surface are discussed. Light and scanning electron micrographs of the microcolonies produced in the laboratory model suggest that the same mechanisms of adhesion, involving extracellular slime, apply as in clinically colonised catheters. Potential uses of the model, for studying further the mechanisms of colonisation and particularly its prevention and treatment, are discussed.

摘要

本文描述了一个金黄色葡萄球菌在硅橡胶导管上定殖的实验室模型。讨论了涉及微生物粘附于管腔表面的真正定殖标准。实验室模型中产生的微菌落的光学和扫描电子显微镜照片表明,与临床定殖导管一样,涉及细胞外黏液的相同粘附机制也适用。讨论了该模型在进一步研究定殖机制,特别是其预防和治疗方面的潜在用途。

相似文献

1
A model of catheter colonisation in vitro and its relationship to clinical catheter infections.体外导管定植模型及其与临床导管感染的关系。
J Infect. 1984 Nov;9(3):271-6. doi: 10.1016/s0163-4453(84)90596-6.
2
Catheter lock solutions influence staphylococcal biofilm formation on abiotic surfaces.导管封管液会影响葡萄球菌在非生物表面形成生物膜。
Nephrol Dial Transplant. 2006 Aug;21(8):2247-55. doi: 10.1093/ndt/gfl170. Epub 2006 Apr 20.
3
[The capability of silicone prostheses to promote postoperative infections. An in-vitro study].[硅橡胶假体促进术后感染的能力。一项体外研究]
Minerva Chir. 1994 Dec;49(12):1299-303.
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Use of an in vitro model for studying the eradication of catheter colonisation by Staphylococcus epidermidis.
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In vitro activity of vancomycin and teicoplanin against Staphylococcus aureus and Staphylococcus epidermidis colonizing catheters.万古霉素和替考拉宁对定植于导管的金黄色葡萄球菌和表皮葡萄球菌的体外活性。
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A morphological study of bacterial colonisation of intravenous cannulae.静脉插管细菌定植的形态学研究
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Adherence of staphylococci to intravascular catheters.葡萄球菌对血管内导管的黏附作用。
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An in vitro model for studying the effects of slime and nonslime-forming Staphylococcus epidermidis contamination of intravenous catheters.一种用于研究黏液型和非黏液型表皮葡萄球菌污染静脉导管影响的体外模型。
Am Surg. 1992 Apr;58(4):220-4.
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In vitro experiments on catheter-related infections due to gram-negative rods.革兰氏阴性杆菌所致导管相关感染的体外实验
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In vitro adherence of Staphylococcus epidermidis to silicone punctual plugs and collagen implants.
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引用本文的文献

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Antifungal activity of amphotericin B, fluconazole, and voriconazole in an in vitro model of Candida catheter-related bloodstream infection.两性霉素B、氟康唑和伏立康唑在念珠菌导管相关血流感染体外模型中的抗真菌活性。
Antimicrob Agents Chemother. 2002 Nov;46(11):3499-505. doi: 10.1128/AAC.46.11.3499-3505.2002.
2
Protein adsorption to hydrocephalus shunt catheters: CSF protein adsorption.蛋白质吸附至脑积水分流导管:脑脊液蛋白质吸附
J Neurol Neurosurg Psychiatry. 1998 May;64(5):643-7. doi: 10.1136/jnnp.64.5.643.
3
Reduced bacterial adhesion to hydrocephalus shunt catheters mediated by cerebrospinal fluid proteins.
脑脊液蛋白介导的细菌对脑积水分流导管黏附力降低。
J Neurol Neurosurg Psychiatry. 1996 Jun;60(6):671-5. doi: 10.1136/jnnp.60.6.671.
4
Cell surface characteristics of coagulase-negative staphylococci and their adherence to fluorinated poly(ethylenepropylene).凝固酶阴性葡萄球菌的细胞表面特征及其对氟化聚(乙烯丙烯)的粘附
Infect Immun. 1986 Jan;51(1):294-301. doi: 10.1128/iai.51.1.294-301.1986.
5
In vitro quantitative model of catheter infection during simulated parenteral nutrition.模拟肠外营养期间导管感染的体外定量模型
J Clin Microbiol. 1988 Sep;26(9):1659-64. doi: 10.1128/jcm.26.9.1659-1664.1988.
6
Physicochemical surface properties of nonencapsulated and encapsulated coagulase-negative staphylococci.非包膜和包膜凝固酶阴性葡萄球菌的物理化学表面特性
Appl Environ Microbiol. 1989 Nov;55(11):2806-14. doi: 10.1128/aem.55.11.2806-2814.1989.
7
Immunochemical analysis of the extracellular slime substance of Staphylococcus epidermidis.表皮葡萄球菌细胞外黏液物质的免疫化学分析
Eur J Clin Microbiol Infect Dis. 1990 Apr;9(4):262-70. doi: 10.1007/BF01968057.
8
Association of coagulase-negative staphylococcal slime production and adherence with the development and outcome of adult septicemias.凝固酶阴性葡萄球菌黏液产生及黏附与成人败血症发生及转归的关系
J Clin Microbiol. 1990 Dec;28(12):2779-85. doi: 10.1128/jcm.28.12.2779-2785.1990.
9
Analysis of the relationship between bacterial adherence and extracellular production of mannose, galactose, glucose and ribose in Staphylococcus epidermidis and Staphylococcus hominis.表皮葡萄球菌和人葡萄球菌中细菌黏附与甘露糖、半乳糖、葡萄糖及核糖胞外产生之间关系的分析
Eur J Clin Microbiol Infect Dis. 1990 Dec;9(12):873-9. doi: 10.1007/BF01967502.