Takamatsu J, Hirano A, Levy D, Henkind P
Neuropathol Appl Neurobiol. 1984 Nov-Dec;10(6):423-8. doi: 10.1111/j.1365-2990.1984.tb00391.x.
The presence of marked changes in the neural retina and retinal vessels of Long-Evans pigmented rat following bilateral carotid ligation has been previously documented by serial ophthalmologic examinations. Light and electron microscopic studies of the optic nerve in this experimental animal model revealed advanced optic nerve atrophy in ten of twelve rats examined. There was no significant pathology in either the retina or optic nerve in the remaining two rats after carotid ligation or in the sham-operated controls.
通过系列眼科检查，先前已证实双侧颈动脉结扎后Long-Evans色素沉着大鼠的神经视网膜和视网膜血管出现明显变化。对该实验动物模型的视神经进行光镜和电镜研究发现，在检查的12只大鼠中，有10只出现了晚期视神经萎缩。在颈动脉结扎后的其余两只大鼠或假手术对照组中，视网膜或视神经均未发现明显病变。
