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人类泪液蛋白质研究。3. 特异性泪液前白蛋白在泪腺及其他眼附属器中的分布。

Studies of human tear proteins. 3. Distribution of specific tear prealbumin in lacrimal glands and other ocular adnexa.

作者信息

Inada K

出版信息

Jpn J Ophthalmol. 1984;28(4):315-30.

PMID:6530834
Abstract

Tear fluid is a mixed solution containing many kinds of proteins, and two predominant fractions have been determined by electrophoretic studies. One is anodal specific tear prealbumin (STP) and the other is cathodal lysozyme. This study is the first to demonstrate the localization of STP in the ocular adnexa by the immunofluorescence method. STP was found in the acinar cells of both the main and the accessory lacrimal glands. The cells of the interlobular ducts showed no or only weak staining of STP. No specific staining of STP was found in the conjunctiva, cornea or Meibomian gland. STP as well as lysozyme are thought to be secreted from the main and the accessory lacrimal glands.

摘要

泪液是一种含有多种蛋白质的混合溶液,通过电泳研究已确定了两种主要成分。一种是阳极特异性泪前白蛋白(STP),另一种是阴极溶菌酶。本研究首次通过免疫荧光法证明了STP在眼附属器中的定位。在主泪腺和副泪腺的腺泡细胞中发现了STP。小叶间导管的细胞未显示或仅显示微弱的STP染色。在结膜、角膜或睑板腺中未发现STP的特异性染色。STP和溶菌酶被认为是由主泪腺和副泪腺分泌的。

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Decreased tear lipocalin concentration in patients with meibomian gland dysfunction.睑板腺功能障碍患者泪液脂质运载蛋白浓度降低。
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Graefes Arch Clin Exp Ophthalmol. 1995 Aug;233(8):513-22. doi: 10.1007/BF00183433.