Nicoletti P
Vaccine. 1984 Jun;2(2):133-5. doi: 10.1016/0264-410x(84)90004-5.
As a result of brucellosis control problems in large Florida dairy herds the use of Brucella abortus strain 19 vaccination has been re-examined. Cattle were vaccinated with different doses of Brucella abortus strain 19 administered by different routes. On the whole, the route of administration was found to have little influence on the efficacy of the vaccine, although the efficacy of vaccine administered orally was difficult to assess. The reduced doses given subcutaneously was selected as the preferred method for adult cattle vaccination.
由于佛罗里达州大型奶牛场布鲁氏菌病控制存在问题，对流产布鲁氏菌19号菌株疫苗的使用进行了重新审视。给牛只接种不同剂量的流产布鲁氏菌19号菌株，并通过不同途径给药。总体而言，尽管口服疫苗的效果难以评估，但发现给药途径对疫苗效果影响不大。皮下注射较低剂量被选为成年牛接种疫苗的首选方法。
