Hansen M, Pedersen N T
Scand J Haematol. 1978 Apr;20(4):371-6. doi: 10.1111/j.1600-0609.1978.tb02469.x.
A total of 21 healthy, adult men and 30 healthy, adult women aged 21-73 years were investigated for circulating megakaryocytes in the antecubital vein using the saponinhaemolysis leucoconcentration technique. In the males, the number of megakaryocytes in 1.5 ml blood varied from 1 to 20, the arithmetic mean being 10 megakaryocytes. In the females the number varied from 0 to 29 megakaryocytes and the arithmetic mean was 7.6 megakaryocytes. No significant difference was found between the values for the two sexes. There was no correlation between the number of megakaryocytes and platelets or leucocytes. 99% of the observed megakaryocytes were naked nuclei or had sparse cytoplasm and 1% had copious cytoplasm. Megakaryocytes without copious cytoplasm may be regarded as normally occurring cells in the peripheral venous blood.
采用皂素溶血白细胞富集技术，对21名年龄在21至73岁之间的健康成年男性和30名健康成年女性的肘前静脉循环巨核细胞进行了研究。在男性中，1.5毫升血液中的巨核细胞数量从1至20个不等，算术平均值为10个巨核细胞。在女性中，巨核细胞数量从0至29个不等，算术平均值为7.6个巨核细胞。两性之间的数值未发现显著差异。巨核细胞数量与血小板或白细胞之间无相关性。观察到的巨核细胞中，99%为裸核或细胞质稀少，1%具有丰富的细胞质。细胞质不丰富的巨核细胞可被视为外周静脉血中的正常细胞。
