Langford H G, Blaufox M D, Oberman A, Hawkins C M, Curb J D, Cutter G R, Wassertheil-Smoller S, Pressel S, Babcock C, Abernethy J D
Trans Assoc Am Physicians. 1984;97:190-6.
The effect of dietary modification on continued blood pressure control after discontinuation of antihypertensive therapy has been studied. Participants who had been treated for 5 years in the Hypertension Detection and Follow-up Program were enrolled and randomly assigned to continue medication, discontinue medication with no dietary intervention, discontinue medication and reduce weight, discontinue medication and reduce sodium groups. Relapse of hypertension was slow, even without dietary modification. Both weight loss and sodium restriction slowed relapse. The severity of the hypertension and the number of drugs required for hypertension control had a marked effect on the rate of relapse. Relapse was slowest in the participants who had attained the lowest blood pressure on therapy.
已对饮食调整对停用抗高血压治疗后持续血压控制的影响进行了研究。在高血压检测与随访项目中接受了5年治疗的参与者被纳入研究，并被随机分配到继续用药组、不进行饮食干预而停药组、停药并减重组、停药并减少钠摄入组。即使不进行饮食调整，高血压的复发也较为缓慢。减重和限制钠摄入均减缓了复发。高血压的严重程度以及控制高血压所需药物的数量对复发率有显著影响。在治疗期间血压降至最低的参与者中，复发最为缓慢。
