• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

增殖性玻璃体视网膜病变:用于抗增殖药物筛选的兔细胞注射模型

Proliferative vitreoretinopathy: the rabbit cell injection model for screening of antiproliferative drugs.

作者信息

Wiedemann P, Sorgente N, Ryan S J

出版信息

J Pharmacol Methods. 1984 Aug;12(1):69-78. doi: 10.1016/0160-5402(84)90008-1.

DOI:10.1016/0160-5402(84)90008-1
PMID:6536816
Abstract

Injection into the rabbit vitreous of cultured cells results in a condition that mimics some of the features of proliferative vitreoretinopathy (PVR) in man. Because of its simplicity and reproducibility, this model is especially useful for screening drugs that may control or inhibit intraocular cell proliferation. The cell injection model of PVR is reviewed, and some modifications are described.

摘要

将培养细胞注入兔玻璃体可导致一种模拟人类增殖性玻璃体视网膜病变(PVR)某些特征的病症。由于其简单性和可重复性,该模型对于筛选可能控制或抑制眼内细胞增殖的药物特别有用。本文综述了PVR的细胞注射模型,并描述了一些改进方法。

相似文献

1
Proliferative vitreoretinopathy: the rabbit cell injection model for screening of antiproliferative drugs.增殖性玻璃体视网膜病变:用于抗增殖药物筛选的兔细胞注射模型
J Pharmacol Methods. 1984 Aug;12(1):69-78. doi: 10.1016/0160-5402(84)90008-1.
2
Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy.
Graefes Arch Clin Exp Ophthalmol. 1992;230(1):66-71. doi: 10.1007/BF00166765.
3
[Evaluation of experimental proliferative vitreoretinopathy in rabbits].
Nippon Ganka Gakkai Zasshi. 1990 Sep;94(9):792-8.
4
Classification of the stages of proliferative vitreoretinopathy in a refined experimental model in the rabbit eye.兔眼精细实验模型中增殖性玻璃体视网膜病变各阶段的分类
Graefes Arch Clin Exp Ophthalmol. 1987;225(4):303-7. doi: 10.1007/BF02150154.
5
Quantitative assessment of growth stimulating activity of the vitreous during PVR.增殖性玻璃体视网膜病变(PVR)期间玻璃体生长刺激活性的定量评估
Invest Ophthalmol Vis Sci. 1992 Jul;33(8):2436-42.
6
Silicone oil as a delivery vehicle for BCNU in rabbit proliferative vitreoretinopathy.
Retina. 1993;13(3):245-50. doi: 10.1097/00006982-199313030-00011.
7
Hyperthermia reduces the occurrence of proliferative vitreoretinopathy in a rabbit model.热疗可降低兔模型中增殖性玻璃体视网膜病变的发生率。
Invest Ophthalmol Vis Sci. 1992 Feb;33(2):404-9.
8
The effect of triamcinolone acetonide on a refined experimental model of proliferative vitreoretinopathy.曲安奈德对增殖性玻璃体视网膜病变精细实验模型的作用
Am J Ophthalmol. 1985 Jun 15;99(6):686-90. doi: 10.1016/s0002-9394(14)76037-4.
9
Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy.
Graefes Arch Clin Exp Ophthalmol. 1991;229(5):464-7. doi: 10.1007/BF00166311.
10
Biodegradable microspheres containing adriamycin in the treatment of proliferative vitreoretinopathy.含阿霉素的可生物降解微球治疗增殖性玻璃体视网膜病变。
Invest Ophthalmol Vis Sci. 1992 Oct;33(11):3125-30.

引用本文的文献

1
Aerosolized, Gas-Phase, Intravitreal Methotrexate Reduces Proliferative Vitreoretinopathy in a Randomized Trial in a Porcine Model.雾化气相玻璃体内注射甲氨蝶呤在猪模型的随机试验中可减轻增殖性玻璃体视网膜病变
Ophthalmol Sci. 2023 Mar 11;3(3):100296. doi: 10.1016/j.xops.2023.100296. eCollection 2023 Sep.
2
Experimental Models to Study Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy.研究增生性玻璃体视网膜病变中上皮-间充质转化的实验模型。
Int J Mol Sci. 2023 Feb 24;24(5):4509. doi: 10.3390/ijms24054509.
3
Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases.
Rho激酶/ROCK作为玻璃体视网膜疾病的潜在药物靶点
J Ophthalmol. 2017;2017:8543592. doi: 10.1155/2017/8543592. Epub 2017 May 10.
4
Intravitreal injection of fibroblasts: the pathological effects on the ocular tissues of the rabbit following an intravitreal injection of autologous skin fibroblasts.玻璃体内注射成纤维细胞:兔玻璃体内注射自体皮肤成纤维细胞后对眼组织的病理影响
Br J Ophthalmol. 1988 Jul;72(7):498-510. doi: 10.1136/bjo.72.7.498.
5
Evaluation of radiation therapy for experimental proliferative vitreoretinopathy in rabbits.
Graefes Arch Clin Exp Ophthalmol. 1990;228(6):552-5. doi: 10.1007/BF00918489.
6
Proliferative vitreoretinopathy--is it anything more than wound healing at the wrong place?增殖性玻璃体视网膜病变——它是否仅仅是在错误部位的伤口愈合?
Int Ophthalmol. 1990 Mar;14(2):105-17. doi: 10.1007/BF00154210.