Bardazzi N, Ciolini P, Donzella A, Curiel P, Da Prada M
Quad Sclavo Diagn. 1984 Dec;20(4):364-71.
A new radioenzymatic assay was used to evaluate free and conjugate catecholamines in six pregnant women who underwent cesarean section at term, in their newborns and in the amniotic fluid. Free adrenaline in maternal plasma was higher while noradrenaline and dopamine were lower at the moment of surgery than 24 hours before the operation. In umbilical plasma adrenaline and noradrenaline are higher than in maternal plasma while only traces of free dopamine and salsolinol are present. In the amniotic fluid high levels of free and conjugated salsolinol are found. The high level of free and conjugated catecholamines found in the umbilical plasma demonstrates that fetal sympathetic nervous system is strongly activated at delivery. Furthermore the presence of sulfoconjugating activity similar to that of the adult is confirmed.
采用一种新的放射酶分析法，对6名足月行剖宫产的孕妇及其新生儿和羊水内的游离和结合儿茶酚胺进行评估。手术时母体血浆中的游离肾上腺素水平较高，而去甲肾上腺素和多巴胺水平低于手术前24小时。脐血浆中的肾上腺素和去甲肾上腺素高于母体血浆，而仅存在微量的游离多巴胺和萨索林醇。羊水中发现高水平的游离和结合萨索林醇。脐血浆中游离和结合儿茶酚胺的高水平表明胎儿交感神经系统在分娩时被强烈激活。此外，还证实存在与成人相似的硫酸结合活性。
