Gilles C, Brucher J M, Khoubesserian P, Vanderhaeghen J J
Neurology. 1984 Jun;34(6):730-5. doi: 10.1212/wnl.34.6.730.
Clinical and pathologic findings in six autopsies and five biopsies of cerebral amyloid angiopathy associated with cerebromeningeal hemorrhages are presented. One patient had experienced a previous meningeal hemorrhage. Only two had chronic hypertension; the multiple fresh hematomas found in all the autopsied brains always spared the basal ganglia and brainstem, as did vascular lesions, which were mostly cortical and meningeal. Extensive lesions of Alzheimer's disease were found in the autopsied cases with dementia. The most significant feature for clinical diagnosis of hemorrhagic cerebral amyloid angiopathy is the presence of multiple hemorrhages in unusual locations in the absence of hypertension.
本文介绍了6例尸检和5例活检的脑淀粉样血管病合并脑脊膜出血的临床和病理表现。1例患者曾有过脑膜出血。仅2例有慢性高血压；在所有尸检大脑中发现的多发性新鲜血肿总是不累及基底节和脑干，血管病变也是如此，这些病变大多位于皮质和脑膜。在有痴呆的尸检病例中发现了广泛的阿尔茨海默病病变。出血性脑淀粉样血管病临床诊断的最重要特征是在无高血压的情况下，在不寻常部位出现多发性出血。
