摄入次氮基三乙酸三钠的雄性大鼠的肾盂和输尿管扩张
Renal pelvic and ureteral dilatation in male rats ingesting trisodium nitrilotriacetate.
作者信息
Kanerva R L, Francis W R, Lefever F R, Dorr T, Alden C L, Anderson R L
出版信息
Food Chem Toxicol. 1984 Sep;22(9):749-53. doi: 10.1016/0278-6915(84)90204-7.
Renal pelvic and proximal ureteral dilatation has been observed in male Charles River (CD) and Fischer 344 rats ingesting comparable doses of Na3NTA X H2O. Ureteral dilatation is accompanied by epithelial surface ulceration and erosion. Taken together with previous work (Anderson, Alden & Merski, Fd Chem. Toxic. 1982, 20, 105), these findings demonstrate that the ingestion of high doses of NTA results in similar effects on the transitional epithelium throughout the urinary tract.
在摄入相当剂量的三水合三钠氮川三乙酸（Na3NTA·H2O）的雄性查尔斯河（CD）大鼠和费希尔344大鼠中，已观察到肾盂和输尿管近端扩张。输尿管扩张伴有上皮表面溃疡和糜烂。结合之前的研究工作（Anderson、Alden和Merski，《食品化学与毒理学》，1982年，20卷，105页），这些发现表明，摄入高剂量的氮川三乙酸会对整个尿路的移行上皮产生类似影响。
Zotero 插件