Della Corte L, Sgaragli G
Pharmacol Res Commun. 1984 Oct;16(10):1041-7. doi: 10.1016/s0031-6989(84)80068-5.
BHA LD50 was determined in mice and rats following i.p. or oral administration, using DMSO or olive oil as vehicle. When DMSO was used, BHA i.p. LD50 was about two orders of magnitude lower as compared to oral LD50. This difference was not so marked when BHA was administered in olive oil.
通过腹腔注射或口服给药,以二甲基亚砜(DMSO)或橄榄油为溶媒,测定了叔丁基对苯二酚(BHA)对小鼠和大鼠的半数致死剂量(LD50)。当使用二甲基亚砜时,与口服LD50相比,腹腔注射BHA的LD50低约两个数量级。当BHA以橄榄油给药时,这种差异并不那么明显。