[Mechanism of action of butylhydroxyanisole (BHA) toxicity: in vivo and in vitro effects on mammalian smooth muscle].
作者信息
Franchi-Micheli S, Della Corte L, Puliti R, Giovannini M G, Zilletti L, Marconi M, Sgaragli G P
出版信息
Boll Soc Ital Biol Sper. 1980 Dec 15;56(23):2521-4.
PMID:7470296
Abstract
The toxicity of butylated hydroxyanisole (BHA) was greatly enhanced in the rat after i.p. administration, the LD50 being two orders of magnitude higher than the oral administered dose. The compound was shown either "in vitro" or "in vivo" to impair the smooth muscle contractility. Study on the mechanism of toxic action of Butylated hydroxyanisole (BHA): "in vivo" and "in vitro" effects on mammalian smooth muscle.
摘要
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