Gonvers J J, Realini S, Bretholz A, Voirol M, Arnold J, Birchler R, Capitaine Y
Schweiz Med Wochenschr. 1984 May 19;114(20):706-8.
37 patients with endoscopically confirmed gastric ulcers received either cimetidine (19 patients) or pirenzepine (18 patients) in a double-blind trial. At 4 weeks, 53% of the patients treated with cimetidine and 44% of those treated with pirenzepine had endoscopically healed ulcers. At 8 weeks, complete healing had occurred in 83% of the patients taking cimetidine and 71% of those taking pirenzepine. These differences are not statistically significant.
在一项双盲试验中,37例经内镜确诊为胃溃疡的患者分别接受了西咪替丁治疗(19例)或哌仑西平治疗(18例)。4周时,接受西咪替丁治疗的患者中有53%的溃疡在内镜检查下愈合,接受哌仑西平治疗的患者中这一比例为44%。8周时,服用西咪替丁的患者中有83%完全愈合,服用哌仑西平的患者中这一比例为71%。这些差异无统计学意义。