DiGiacomo R F, Lukehart S A, Talburt C D, Baker-Zander S A, Condon J, Brown C W
Br J Vener Dis. 1984 Aug;60(4):214-8. doi: 10.1136/sti.60.4.214.
Ten sporadic cases of venereal spirochaetosis, caused by Treponema paraluis-cuniculi, were seen in New Zealand white rabbits in two years. An equal number of males and females were affected. Females tended to have milder clinical signs than males. Lesions were usually found on the prepuce in males and the vulva in females, although the anus and skin of the perineum were also affected. Facial lesions were rare. Lesions healed in seven to 28 days in rabbits treated with penicillin. Eight rabbits had antibodies reactive in the Venereal Disease Research Laboratory (VDRL), rapid plasma reagin (RPR), and fluorescent treponemal antibody absorbed (FTA-ABS) tests when the disease was first diagnosed. In several rabbits followed longitudinally, RPR test results became negative two to four months after antimicrobial treatment, VDRL antibody titres diminished but usually persisted at low levels, while FTA-ABS antibodies declined slowly and were still evident 12 months after treatment.
两年内,在新西兰白兔中发现了10例由兔梅毒螺旋体引起的散发性性病螺旋体病病例。雄性和雌性受影响的数量相等。雌性的临床症状往往比雄性轻。病变通常见于雄性的包皮和雌性的外阴,不过肛门和会阴皮肤也会受到影响。面部病变很少见。用青霉素治疗的兔子的病变在7至28天内愈合。首次诊断疾病时,8只兔子在性病研究实验室(VDRL)、快速血浆反应素(RPR)和荧光密螺旋体抗体吸收(FTA-ABS)试验中出现抗体反应。在几只纵向跟踪的兔子中,抗菌治疗后两到四个月,RPR检测结果变为阴性,VDRL抗体滴度降低但通常仍维持在低水平,而FTA-ABS抗体下降缓慢,治疗12个月后仍很明显。