Cunliffe-Beamer T L, Fox R R
Lab Anim Sci. 1981 Aug;31(4):372-8.
Venereal spirochetosis of rabbits was studied in an enzootically infected conventional rabbit colony. Differences in the susceptibility to and expression of venereal spirochetosis among different inbred or partially inbred strains of rabbits were observed. Significant differences between frequency of lesions in adult male or female rabbits were not observed. Significant differences between the frequency of lesions in breeders or non-breeders were not observed in the 6-12 month age group. However, significant differences between the frequency of lesions in breeders and non-breeders were observed when different ages were pooled. The frequency of venereal spirochetosis in rabbits less than 6 months of age was lower than that in adult rabbits. Newborn fostering experiments indicated that infection occurred at birth and during the suckling period. Evaluation of hysterectomy-derived offspring of infected dams suggested venereal spirochetosis was eliminated by hysterectomy-derivation. Venereal spirochetosis was successfully transmitted by topical or intradermal-subcutaneous genital inoculation of adult rabbits. Adult rabbits were more susceptible to experimental venereal spirochetosis than neonates. The above conclusions were based on clinical and serological observations.
在一个自然感染的传统兔群中对兔性病螺旋体病进行了研究。观察到不同近交或部分近交兔品系之间在兔性病螺旋体病易感性和表现方面的差异。未观察到成年雄兔或雌兔病变频率的显著差异。在6至12月龄组中，未观察到种兔或非种兔病变频率的显著差异。然而，当合并不同年龄时，观察到种兔和非种兔病变频率的显著差异。6月龄以下兔的性病螺旋体病发病率低于成年兔。新生兔寄养实验表明，感染发生在出生时和哺乳期。对感染母兔子宫切除所产后代的评估表明，子宫切除可消除兔性病螺旋体病。通过对成年兔进行局部或皮内-皮下生殖器接种，成功传播了兔性病螺旋体病。成年兔比新生兔对实验性兔性病螺旋体病更易感。上述结论基于临床和血清学观察。
