黑甲虫病毒RNA2的一级和二级结构，BBV衣壳蛋白前体的基因组信使。
Primary and secondary structure of black beetle virus RNA2, the genomic messenger for BBV coat protein precursor.
作者信息
Dasgupta R, Ghosh A, Dasmahapatra B, Guarino L A, Kaesberg P
出版信息
Nucleic Acids Res. 1984 Sep 25;12(18):7215-23. doi: 10.1093/nar/12.18.7215.
Abstract
The nucleotide sequence of black beetle virion (BBV) RNA2 has been determined. RNA2 is 1399 b long. Its 5' terminus is capped. Its 3' terminus has an unidentified moiety that renders the RNA resistent to polyadenylation and ligation. The first AUG codon at base 23 is followed by an open reading frame for a protein 407 amino acids long, the predicted size of coat protein precursor. A second open reading frame for a putative protein 72 amino acid residues long begins at base 1110. No other large open reading frames exist. The 5' half of the RNA can be folded into a long, imperfect hairpin of high predicted stability. The 3' half of the RNA can fold into a complex set of multiply bifurcated stem and loop regions.
摘要
黑甲虫病毒粒子（BBV）RNA2的核苷酸序列已被确定。RNA2长1399个碱基对。其5'末端有帽结构。其3'末端有一个未知部分，使RNA对聚腺苷酸化和连接具有抗性。位于第23位碱基的第一个AUG密码子之后是一个407个氨基酸长的蛋白质的开放阅读框，这是衣壳蛋白前体的预测大小。一个推测的72个氨基酸残基长的蛋白质的第二个开放阅读框始于第1110位碱基。不存在其他大的开放阅读框。RNA的5'半段可折叠成一个长的、不完全的发夹结构，预测稳定性高。RNA的3'半段可折叠成一组复杂的多重分支的茎环区域。
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