Estimation of endpoints in biological systems.

A program, written in BASIC, has been developed to estimate rapidly endpoints from a small number of experimental data. The computational method is based on the work of Reed and Muench (Am. J. Hyg. 27, 493 1938). Several endpoints may be estimated in the same run. A subroutine allows the saving of experimental data in disk file and a printout subroutine permits different types of printout (tabular or graphical). Estimation of several infectious doses (ID) of a guinea-pig inclusion conjunctivitis (GPIC) Chlamydia psittaci strain is given as sample run.