Mondino B J, Rao H
Invest Ophthalmol Vis Sci. 1983 Mar;24(3):380-4.
C2, C6, and C7 were measured by hemolytic assay and Factor B and IgG were measured by radial immunodiffusion in samples of normal and inflamed aqueous humor. Normal aqueous humor was found to contain functional C2, C6, and C7, but the small ratios of aqueous humor to serum measurements suggested that there was relatively little of these complement components in normal aqueous humor when compared to serum. The mean values of C2, C6, C7, and Factor B in aqueous humor and the median ratios of aqueous humor to serum measurements for each complement component were higher in patients with inflamed aqueous humor than in patients with normal aqueous humor. A comparison of the ratios of IgG to each complement component in normal and inflamed aqueous humor suggested that levels of IgG and complement increased proportionately in inflamed aqueous humor. Factor B, a component of the alternative pathway, was not detected in normal aqueous humor but measured in five of six samples of aqueous humor from eyes with anterior chamber inflammation.
通过溶血试验测定C2、C6和C7，并通过放射免疫扩散法测定正常和发炎房水样本中的B因子和IgG。发现正常房水含有功能性C2、C6和C7，但房水与血清测量值的比例较小，这表明与血清相比，正常房水中这些补体成分相对较少。发炎房水患者房水中C2、C6、C7和B因子的平均值以及每种补体成分的房水与血清测量值的中位数比例均高于正常房水患者。正常和发炎房水中IgG与每种补体成分比例的比较表明，发炎房水中IgG和补体水平成比例增加。替代途径的成分B因子在正常房水中未检测到，但在六个前房炎症眼房水样本中的五个中检测到。
