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尿毒症性肺水肿

Uremic pulmonary edema.

作者信息

Rackow E C, Fein I A, Sprung C, Grodman R S

出版信息

Am J Med. 1978 Jun;64(6):1084-8. doi: 10.1016/0002-9343(78)90466-7.

DOI:10.1016/0002-9343(78)90466-7
PMID:655190
Abstract

Pulmonary edema fluid analyses and hemodynamic evaluations were performed in two uremic patients with acute pulmonary edema. The colloid osmotic pressure of the pulmonary edema fluid ranged from 57 per cent to 93 per cent that of the serum. Although cardiac function was normal in both patients, the serum colloid osmotic pressure--pulmonary artery wedge pressure gradients were markedly reduced. Uremic pulmonary edema is the result of alterations of pulmonary intravascular Starling forces and increases in pulmonary capillary membrane permeability, allowing for the efflux of protein-rich fluid from the capillaries into the lung.

摘要

对两名患有急性肺水肿的尿毒症患者进行了肺水肿液分析和血流动力学评估。肺水肿液的胶体渗透压为血清胶体渗透压的57%至93%。尽管两名患者的心功能均正常,但血清胶体渗透压与肺动脉楔压梯度均明显降低。尿毒症性肺水肿是肺血管内斯塔林力改变以及肺毛细血管膜通透性增加的结果,使得富含蛋白质的液体从毛细血管流入肺内。

相似文献

1
Uremic pulmonary edema.尿毒症性肺水肿
Am J Med. 1978 Jun;64(6):1084-8. doi: 10.1016/0002-9343(78)90466-7.
2
Pulmonary edema related to changes in colloid osmotic and pulmonary artery wedge pressure in patients after acute myocardial infarction.急性心肌梗死后患者胶体渗透压和肺动脉楔压变化相关的肺水肿
Circulation. 1975 Feb;51(2):350-7. doi: 10.1161/01.cir.51.2.350.
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Evidence for increased permeability in reexpansion pulmonary edema.复张性肺水肿中通透性增加的证据。
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Fulminant noncardiogenic pulmonary edema in the critically ill.危重症患者的暴发性非心源性肺水肿
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Hemodynamic and alveolar protein studies in noncardiac pulmonary edema.非心源性肺水肿的血流动力学和肺泡蛋白研究
Am Rev Respir Dis. 1976 Nov;114(5):831-5. doi: 10.1164/arrd.1976.114.5.831.
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Hemodynamic observations in severe preeclampsia complicated by pulmonary edema.重度子痫前期合并肺水肿的血流动力学观察
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Relationship between colloid osmotic pressure and pulmonary artery wedge pressure in patients with acute cardiorespiratory failure.急性心肺功能衰竭患者胶体渗透压与肺动脉楔压的关系
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J Clin Invest. 2025 May 15;135(10). doi: 10.1172/JCI192917.
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Acute kidney injury triggers hypoxemia by lung intravascular neutrophil retention that reduces capillary blood flow.急性肾损伤通过肺血管内中性粒细胞滞留导致低氧血症,进而减少毛细血管血流。
J Clin Invest. 2025 Mar 6;135(10). doi: 10.1172/JCI186705. eCollection 2025 May 15.
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肾脏-肺部轴中的器官间通讯网络。
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J Nephrol. 2023 May;36(4):1037-1046. doi: 10.1007/s40620-022-01558-9. Epub 2023 Jan 24.
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Mechanisms and mediators of lung injury after acute kidney injury.急性肾损伤后肺损伤的机制和介质。
Nat Rev Nephrol. 2016 Jan;12(1):48-60. doi: 10.1038/nrneph.2015.158. Epub 2015 Oct 6.
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Prolonged acute kidney injury exacerbates lung inflammation at 7 days post-acute kidney injury.急性肾损伤延长会在急性肾损伤后7天加重肺部炎症。
Physiol Rep. 2014 Jul 22;2(7). doi: 10.14814/phy2.12084. Print 2014 Jul 1.
7
Thoracic complications in uremic patients and in patients undergoing dialytic treatment: state of the art.尿毒症患者及接受透析治疗患者的胸部并发症:最新进展
Eur Radiol. 1997;7(5):708-17. doi: 10.1007/BF02742931.
8
The lungs in uraemia: a review.尿毒症中的肺部病变:综述
J R Soc Med. 1985 Oct;78(10):849-55. doi: 10.1177/014107688507801012.
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Pulmonary vascular permeability to transferrin in the pulmonary oedema of renal failure.肾衰竭肺水肿时肺血管对转铁蛋白的通透性
Thorax. 1987 Aug;42(8):620-3. doi: 10.1136/thx.42.8.620.
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Effect of uremia and its treatment on pulmonary function.尿毒症及其治疗对肺功能的影响。
Lung. 1990;168(1):1-14. doi: 10.1007/BF02719668.