耐甲氧西林金黄色葡萄球菌菌株中耐甲氧西林的隔膜肽聚糖合成
Methicillin-resistant septal peptidoglycan synthesis in a methicillin-resistant Staphylococcus aureus strain.
作者信息
Wilkinson B J, Nadakavukaren M J
出版信息
Antimicrob Agents Chemother. 1983 Apr;23(4):610-3. doi: 10.1128/AAC.23.4.610.
Abstract
In a methicillin-resistant Staphylococcus aureus strain, electron micrographs showed that cell wall septa continued to be formed in the presence of methicillin, although they became distorted and enlarged. The results indicated that peripheral cell wall synthesis was inhibited. It is concluded that a methicillin-resistant mode of septal peptidoglycan synthesis is an important determinant of methicillin resistance.
摘要
在一株耐甲氧西林金黄色葡萄球菌中，电子显微镜照片显示，尽管细胞壁隔膜在甲氧西林存在的情况下会变得扭曲和增大，但仍会继续形成。结果表明外周细胞壁合成受到抑制。得出的结论是，隔膜肽聚糖合成的耐甲氧西林模式是耐甲氧西林的一个重要决定因素。
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