de Jonge B L, Tomasz A
Rockefeller University, New York, New York 10021.
Antimicrob Agents Chemother. 1993 Feb;37(2):342-6. doi: 10.1128/AAC.37.2.342.
Upon the addition of methicillin even at relatively low concentrations (5 mug/ml or 0.3% of the MIC) to the medium, methicillin-resistant staphylococci shift to the production of a new peptidoglycan with an abnormal muropeptide composition which may be the synthetic product of penicillin-binding protein 2A.
即便在培养基中加入相对低浓度的甲氧西林(5微克/毫升或最低抑菌浓度的0.3%),耐甲氧西林葡萄球菌也会转而产生一种具有异常肽聚糖组成的新型肽聚糖,这可能是青霉素结合蛋白2A的合成产物。