Davin J C, Foidart J B, Mahieu P R
Proc Eur Dial Transplant Assoc. 1983;19:590-6.
The Fc-receptor function of circulating monocytes (CM) and/or of splenic macrophages (SM) was followed in eight children presenting with rheumatoid purpura. The Fc-receptor of CM and/or of SM was decreased in all cases during the acute phase of the disease without any correlation with the plasma values of C3, C4, C3PA or immune complexes. When a clinical improvement occurred, a reversal of the Fc-receptor blockade was noted. In contrast, the Fc-receptor function remained abnormal in three children with persistent nephritis. The sequential measurement of Fc-receptor function may be of predictive value in rheumatoid purpura of childhood.
对8例患有类风湿性紫癜的儿童的循环单核细胞（CM）和/或脾巨噬细胞（SM）的Fc受体功能进行了跟踪研究。在疾病急性期，所有病例中CM和/或SM的Fc受体均降低，且与C3、C4、C3PA或免疫复合物的血浆值无任何相关性。当临床症状改善时，Fc受体阻断出现逆转。相比之下，3例持续性肾炎患儿的Fc受体功能仍异常。Fc受体功能的连续测量可能对儿童类风湿性紫癜具有预测价值。
