Cunha-Vaz J G, Lima J J
Arch Ophthalmol. 1978 May;96(5):893-7. doi: 10.1001/archopht.1978.03910050495022.
This article describes a new direct method for estimation of human retinal blood flow by slit-lamp fluorophotometry. The apparatus consists fundamentally of a modified slit lamp with an eye piece containing two fiberoptic probes connected to a double photometric detection system. Both optic fibers are focused on a retinal arterial segment, and the passage of a fluorescein bolus is automatically registered, giving, after correction, the mean transit time. Fluorescein angiography allows the determination of the volume of the arterial segment under study. Values for superior temporal retinal blood flow in healthy individuals show a mean value of 4.2 +/- 0.5 microliter/min. Studies in anemic patients show an increase of approximately 52% in the retinal blood flow. The potential causes of error associated with this technique, apart from the slight increase in intraocular pressure induced by the contact lens used, do not appear to be significant.
本文介绍了一种通过裂隙灯荧光光度法估算人体视网膜血流量的新直接方法。该仪器主要由一台改良的裂隙灯组成，其目镜包含两个连接到双光度检测系统的光纤探头。两根光纤都聚焦在视网膜动脉段上，荧光素团块的通过会自动记录下来，经过校正后得出平均通过时间。荧光素血管造影可确定所研究动脉段的容积。健康个体颞上视网膜血流量的值显示平均值为4.2±0.5微升/分钟。对贫血患者的研究表明视网膜血流量增加了约52%。除了所用隐形眼镜引起的眼压略有升高外，与该技术相关的潜在误差原因似乎并不显著。
