葡萄球菌对甲氧西林和头孢菌素的交叉耐药性：头孢孟多并非普遍存在的假设情况。
Cross-resistance between methicillin and cephalosporins for staphylococci: a general assumption not true for cefamandole.
作者信息
Frongillo R F, Bianchi P, Moretti A, Pasticci M B, Ripa S, Pauluzzi S
出版信息
Antimicrob Agents Chemother. 1984 May;25(5):666-8. doi: 10.1128/AAC.25.5.666.
Abstract
The antibacterial activity of cefamandole was evaluated against 120 methicillin-susceptible and methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococcal strains, using both large (10(8) CFU per ml) and small (10(4) CFU per ml) inocula. Cefamandole appeared superior to cephalothin against methicillin-resistant strains, displaying at 10 micrograms/ml a bacteriostatic and for some strains a bactericidal action against a large inoculum of bacteria.
摘要
使用大接种量（每毫升10⁸ 菌落形成单位）和小接种量（每毫升10⁴ 菌落形成单位），对120株甲氧西林敏感和耐甲氧西林金黄色葡萄球菌及凝固酶阴性葡萄球菌菌株评估了头孢孟多的抗菌活性。在针对耐甲氧西林菌株方面，头孢孟多似乎优于头孢噻吩，在10微克/毫升时对大量细菌接种物显示出抑菌作用，对某些菌株还显示出杀菌作用。
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