Blinkhorn A S, Holloway P J, Davies T G
Community Dent Oral Epidemiol. 1983 Feb;11(1):7-11. doi: 10.1111/j.1600-0528.1983.tb01347.x.
751 14- and 15-year old children completed a 3-year, double-blind, caries preventive program. The effects of daily, supervised toothbrushing with an 0.76% sodium monofluorophosphate dentifrice, rinsing with a 0.05% sodium fluoride mouthrinse, and the combined effects of the two treatments were investigated. Both the dentifrice and mouthrinse reduced the incidence of dental caries, but their combined use at the same time had no greater effect than either used alone.
751名14至15岁的儿童完成了一项为期3年的双盲龋齿预防项目。研究了每日在监督下使用含0.76%单氟磷酸钠的牙膏刷牙、用含0.05%氟化钠的漱口水漱口的效果,以及两种治疗方法的联合效果。牙膏和漱口水都降低了龋齿的发病率,但同时使用它们的效果并不比单独使用其中任何一种更好。