澳大利亚的德尔塔相关肝炎

Delta associated hepatitis in Australia.

作者信息

Williams G V, Cossart Y E

出版信息

Aust N Z J Med. 1983 Jun;13(3):231-5. doi: 10.1111/j.1445-5994.1983.tb04649.x.

DOI:10.1111/j.1445-5994.1983.tb04649.x

Abstract

Hepatitis B associated delta infection was found in Australian born narcotics users, patients with cirrhosis and hepatoma from Italy and Greece and in south east Asian immigrants. About 9% of patients with chronic hepatitis B were found to have intranuclear delta antigen in liver biopsies with immunofluorescence or anti-delta antibody in serum by radioimmunoassay. Delta may have been imported from southern Europe and Asia and a reservoir of delta infection may exist in narcotics users. Anti-delta was not found in hemophiliacs despite exposure to hepatitis B. Delta occurs in Australia and causes acute and particularly chronic hepatitis in addition to that caused by hepatitis B.

摘要

在澳大利亚出生的吸毒者、来自意大利和希腊的肝硬化及肝癌患者以及东南亚移民中发现了与乙肝相关的丁型感染。通过免疫荧光法对肝活检组织进行检测，或采用放射免疫分析法检测血清中的抗丁型抗体，结果发现约9%的慢性乙肝患者肝活检组织中存在核内丁型抗原。丁型感染可能是从南欧和亚洲传入的，吸毒者中可能存在丁型感染的传染源。尽管血友病患者接触过乙肝病毒，但未检测到抗丁型抗体。丁型感染在澳大利亚存在，除了乙肝引发的肝炎外，还会导致急性肝炎，尤其是慢性肝炎。