Clarkson B H, Wefel J S, Miller I
J Dent Res. 1984 Jan;63(1):13-8. doi: 10.1177/00220345840630010101.
The ability of metal ion mordanting followed by APF application to inhibit the progression of caries-like lesions was compared with APF treatment alone. The progression of the lesion was investigated in vitro using an acidified gel system, and the lesions were compared using polarized light microscopy. Both ferric and zirconyl pre-treatments, but not titanium, were shown to inhibit lesion progression to a greater extent than did APF. This inhibition was thought to be due to the presence of an amorphous-type coating similar to those produced on sound enamel by metal ion mordanting.
将金属离子媒染后应用酸性磷酸氟（APF）抑制龋样病变进展的能力与单独使用APF治疗进行了比较。使用酸化凝胶系统在体外研究病变的进展，并使用偏光显微镜对病变进行比较。结果显示，铁和锆预处理（而非钛预处理）比APF能更大程度地抑制病变进展。这种抑制作用被认为是由于存在一种无定形涂层，类似于金属离子媒染在健康牙釉质上产生的涂层。
