Clarkson B H, Wefel J S, Miller I, Edie J
J Dent Res. 1984 Feb;63(2):106-10. doi: 10.1177/00220345840630020101.
The production of tenacious surface coatings on enamel after metal ion mordanting followed by APF has been reported to prevent caries-like lesion initiation in vitro. In this study, similar surface coatings, which may be responsible for the inhibition of lesion progression, were examined using SEM and microprobe analysis. Relatively thick, even surface coatings which were in intimate contact with the enamel surface of caries-like lesions were seen after zirconium and iron (ferric) pre-treatment, but a thinner and unevenly distributed coating was seen after titanium pre-treatment. This latter coating was similar to that seen after APF treatment alone. Fluoride concentrations on the surface and in the subsurface of caries-like lesions were similar for all treatment groups. The surface coatings after zirconium and iron mordanting may be responsible for the greater inhibition of lesion progression than that seen after both titanium pre-treatment and APF treatment alone.
据报道，在金属离子媒染后再进行含氟磷酸（APF）处理，可在牙釉质上形成坚韧的表面涂层，从而在体外预防龋样病变的发生。在本研究中，使用扫描电子显微镜（SEM）和微探针分析对可能抑制病变进展的类似表面涂层进行了检查。经过锆和铁（三价铁）预处理后，观察到相对较厚且均匀的表面涂层与龋样病变的牙釉质表面紧密接触，但经过钛预处理后，涂层较薄且分布不均。后一种涂层与单独进行APF处理后观察到的涂层相似。所有治疗组龋样病变表面和次表面的氟浓度相似。与钛预处理和单独进行APF处理相比，锆和铁媒染后的表面涂层可能对病变进展具有更大的抑制作用。
