人混合唾液中花生四烯酸代谢物的浓度与流速无关。

Concentrations of arachidonic-acid metabolites in human mixed saliva are independent of flow rate.

作者信息

Rigas B, Levine L

出版信息

Arch Oral Biol. 1983;28(12):1135-7. doi: 10.1016/0003-9969(83)90171-1.

Abstract

Three prostaglandins, PGE2, PGF2 alpha and PGI2 (measured as 6-keto-PGF1 alpha), serologically active 6-sulphidopeptide-containing leukotrienes and hydroxyeicosatetraenoic acids were determined by radioimmunoassay of mixed saliva obtained at several flow rates from 8 healthy volunteers. Flow rates ranged from 0.26 +/- 0.02 ml/min when saliva production was unstimulated to 1.18 +/- 0.14 ml/min (values mean +/- SEM) when maximally stimulated. Concentrations of all compounds tested remained independent of changes in mixed-saliva flow rate.

摘要

通过放射免疫分析法测定了8名健康志愿者在不同流速下采集的混合唾液中的三种前列腺素（PGE2、PGF2α和PGI2，以6-酮-PGF1α衡量）、具有血清学活性的含6-硫代肽白三烯和羟基二十碳四烯酸。流速范围从不刺激唾液分泌时的0.26±0.02毫升/分钟到最大刺激时的1.18±0.14毫升/分钟（数值为平均值±标准误）。所有测试化合物的浓度均与混合唾液流速的变化无关。