兔、大鼠和人唾液中花生四烯酸代谢产物的鉴定与定量分析。
Identification and quantitation of arachidonic-acid metabolic products in rabbit, rat and human saliva.
作者信息
Rigas B, Lewis R A, Austen K F, Corey E J, Levine L
出版信息
Arch Oral Biol. 1983;28(11):1031-5. doi: 10.1016/0003-9969(83)90058-4.
Arachidonic-acid metabolites were identified in salivary secretions of rabbits, rats and man and in homogenates of rabbit parotid and submandibular glands. The following levels were determined in mixed saliva of healthy volunteers: PGE2, 0.65 +/- 0.8 ng/ml; PGF2 alpha, 0.41 +/- 0.06 ng/ml; serologically active hydroxyeicosatetraenoic acids (HETE) 319.6 +/- 36.6 ng/ml; serologically active 6-sulphidopeptide-containing leukotrienes 1.72 +/- 0.21 ng/ml (all values mean +/- SEM). In all instances, HETE markedly predominated over all other arachidonic-acid metabolites.
在兔、大鼠和人的唾液分泌物以及兔腮腺和颌下腺匀浆中鉴定出了花生四烯酸代谢物。测定了健康志愿者混合唾液中的以下水平：前列腺素E2（PGE2），0.65±0.8纳克/毫升；前列腺素F2α（PGF2α），0.41±0.06纳克/毫升；血清学活性羟基二十碳四烯酸（HETE）319.6±36.6纳克/毫升；血清学活性含6-硫肽白三烯1.72±0.21纳克/毫升（所有数值均为平均值±标准误）。在所有情况下，HETE在所有其他花生四烯酸代谢物中占明显优势。
Zotero 插件