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人体食物在小肠中的通过时间:测量、调节及可能的重要性。

Small bowel transit time of food in man: measurement, regulation and possible importance.

作者信息

Read N W

出版信息

Scand J Gastroenterol Suppl. 1984;96:77-85.

PMID:6591384
Abstract

Studies on the relevance of scintigraphy and breath hydrogen analysis to the measurement of small bowel transit time are outlined. The main dietary factor influencing small bowel transit time appears to be the level of unabsorbable carbohydrate. The rates of gastric emptying and small bowel transit seem to be largely independent of one another. A weak correlation exists between the time for 50% of a meal to enter the caecum and the contraction frequency of the upper jejunum. Unabsorbed food in the ileum may increase the period over which material remains in the small intestine. Absorption cannot be predicted from a knowledge of transit kinetics alone. Diarrhoea may arise if rapid small bowel transit causes unduly rapid entry of fluid into the colon. In the irritable bowel syndrome, accelerated small bowel transit occurs in patients with diarrhoea.

摘要

本文概述了闪烁扫描法和呼气氢分析与小肠转运时间测量相关性的研究。影响小肠转运时间的主要饮食因素似乎是不可吸收碳水化合物的水平。胃排空率和小肠转运率似乎在很大程度上相互独立。一餐中50%进入盲肠的时间与空肠上段的收缩频率之间存在微弱的相关性。回肠中未吸收的食物可能会延长物质在小肠内停留的时间。仅根据转运动力学知识无法预测吸收情况。如果小肠快速转运导致液体过度快速进入结肠,可能会引发腹泻。在肠易激综合征中,腹泻患者会出现小肠转运加速的情况。

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Small bowel transit time of food in man: measurement, regulation and possible importance.人体食物在小肠中的通过时间:测量、调节及可能的重要性。
Scand J Gastroenterol Suppl. 1984;96:77-85.
2
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Fructose and sorbitol malabsorption in ambulatory patients with functional dyspepsia: comparison with lactose maldigestion/malabsorption.门诊功能性消化不良患者的果糖和山梨醇吸收不良:与乳糖消化/吸收不良的比较。
Dig Dis Sci. 1997 Dec;42(12):2591-8. doi: 10.1023/a:1018841402133.
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Lactulose hydrogen breath test in orocecal transit assessment. Critical evaluation by means of scintigraphic method.乳果糖氢呼气试验在口盲肠转运评估中的应用。通过闪烁扫描法进行的批判性评价。
Dig Dis Sci. 1994 Jul;39(7):1505-10. doi: 10.1007/BF02088056.
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Evaluation of gastrointestinal motility using the hydrogen breath test.
使用氢呼气试验评估胃肠动力。
Br J Clin Pharmacol. 1985 Nov;20(5):479-81. doi: 10.1111/j.1365-2125.1985.tb05101.x.
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Transit of pharmaceutical dosage forms through the small intestine.药物剂型在小肠中的转运。
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Barbiturate poisoning and gastrointestinal propulsion.巴比妥类药物中毒与胃肠推进
Arch Toxicol. 1987 Jul;60(5):394-6. doi: 10.1007/BF00295761.
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Tropical sprue--its aetiology and pathogenesis.热带口炎性腹泻——其病因与发病机制
J R Soc Med. 1986 Oct;79(10):599-606. doi: 10.1177/014107688607901015.
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Gastrointestinal transit of a solid indigestible capsule as measured by radiotelemetry and dual gamma scintigraphy.通过无线电遥测和双伽马闪烁扫描法测量固体不可消化胶囊在胃肠道中的转运情况。
Pharm Res. 1989 Aug;6(8):719-24. doi: 10.1023/a:1015998708560.
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