Ruckdeschel G, Ehret W, Ahl A
Eur J Clin Microbiol. 1984 Oct;3(5):463-7. doi: 10.1007/BF02017376.
With 28 beta-lactam antibiotics the susceptibilities of 60 strains of Legionella spp. (49 Legionella pneumophila and 11 ATCC type strains of other Legionella species) were determined. Agar dilution testing was used on buffered charcoal-yeast extract agar to which 0.1% alpha-ketoglutarate was added. The most active of the penicillins tested were ampicillin (MIC = 0.06-8 mg/l) and temocilin (MIC = 0.125 - 16 mg/l); the most active cephalosporins were ceftazidime (MIC = 0.03 - 0.5 mg/l), HR 810 (MIC = 0.06 - 1 mg/l) and cefoxitin (MIC = 0.125 - 2 mg/l). Of all the drugs tested imipenem had the most pronounced activity (MIC = .0075 - 0.06 mg/l).
采用28种β-内酰胺类抗生素对60株军团菌属菌株（49株嗜肺军团菌和11株其他军团菌属的ATCC标准菌株）进行药敏试验。在添加了0.1%α-酮戊二酸的缓冲活性炭酵母浸出液琼脂上，采用琼脂稀释法进行检测。所测试的青霉素类中活性最强的是氨苄西林（MIC=0.06 - 8mg/L）和替莫西林（MIC=0.125 - 16mg/L）；头孢菌素类中活性最强的是头孢他啶（MIC=0.03 - 0.5mg/L）、HR 810（MIC=0.06 - 1mg/L）和头孢西丁（MIC=0.125 - 2mg/L）。在所测试的所有药物中，亚胺培南的活性最为显著（MIC=0.0075 - 0.06mg/L）。
