匹兹堡肺炎病原体（米德戴军团菌）及军团菌属其他新确认成员对19种抗菌药物的敏感性。
Susceptibility of Pittsburgh pneumonia agent (Legionella micdadei) and other newly recognized members of the genus Legionella to nineteen antimicrobial agents.
作者信息
Pasculle A W, Dowling J N, Weyant R S, Sniffen J M, Cordes L G, Gorman G M, Feeley J C
出版信息
Antimicrob Agents Chemother. 1981 Dec;20(6):793-9. doi: 10.1128/AAC.20.6.793.
Abstract
The susceptibilities of 11 strains representing the five recognized species of Legionella were determined by agar dilution testing on buffered charcoal-yeast extract agar. All of the legionellae tested were susceptible to rifampin, erythromycin, rosaramycin, chloramphenicol, and the aminoglycosides and were resistant to clindamycin and vancomycin. Susceptibilities to penicillins and cephalosporins were variable. Legionella micdadei, Legionella bozemanii, and Legionella gormanii were susceptible to these agents, but minimal inhibitory concentrations for each species were different. Legionella dumoffii resembled Legionella pneumophila in being resistant to penicillin, cephalothin, and cephamandole and susceptible to moxalactam and cefoxitin. All species except L. micdadei produced beta-lactamase.
摘要
通过在缓冲活性炭酵母提取物琼脂上进行琼脂稀释试验，测定了代表军团菌属五个公认菌种的11株菌株的药敏性。所有受试军团菌对利福平、红霉素、罗沙霉素、氯霉素和氨基糖苷类敏感，对克林霉素和万古霉素耐药。对青霉素和头孢菌素的药敏性各不相同。米克戴德军团菌、博兹曼军团菌和戈尔曼军团菌对这些药物敏感，但每个菌种的最低抑菌浓度不同。杜莫夫军团菌与嗜肺军团菌相似，对青霉素、头孢噻吩和头孢孟多耐药，对莫西沙星和头孢西丁敏感。除米克戴德军团菌外，所有菌种均产生β-内酰胺酶。
相似文献
1
Susceptibility of Pittsburgh pneumonia agent (Legionella micdadei) and other newly recognized members of the genus Legionella to nineteen antimicrobial agents.匹兹堡肺炎病原体（米德戴军团菌）及军团菌属其他新确认成员对19种抗菌药物的敏感性。
Antimicrob Agents Chemother. 1981 Dec;20(6):793-9. doi: 10.1128/AAC.20.6.793.
2
Disk diffusion antimicrobial susceptibility testing of members of the family Legionellaceae including erythromycin-resistant variants of Legionella micdadei.军团菌科成员的纸片扩散法抗菌药物敏感性试验，包括米克戴德军团菌的耐红霉素变异株。
J Clin Microbiol. 1984 Jun;19(6):723-9. doi: 10.1128/jcm.19.6.723-729.1984.
3
In vitro antibiotic susceptibility of Legionellaceae: search for alternative antimicrobial drugs.军团菌科的体外抗生素敏感性：寻找替代抗菌药物
Chemotherapy. 1984;30(3):182-7. doi: 10.1159/000238266.
4
Susceptibility of Legionella pneumophila to twenty antimicrobial agents.嗜肺军团菌对二十种抗菌药物的敏感性
Antimicrob Agents Chemother. 1980 Sep;18(3):403-8. doi: 10.1128/AAC.18.3.403.
5
[Practical problems raised by antibiotic minimal inhibitory concentration determination in Legionella species (author's transl)].军团菌属抗生素最低抑菌浓度测定引发的实际问题（作者译）
Pathol Biol (Paris). 1982 Jun;30(6):421-5.
6
Bactericidal activity of antibiotics against Legionella micdadei (Pittsburgh pneumonia agent).抗生素对米克戴德军团菌（匹兹堡肺炎病原体）的杀菌活性。
Antimicrob Agents Chemother. 1982 Aug;22(2):272-6. doi: 10.1128/AAC.22.2.272.
7
Application of the Etest to antimicrobial susceptibility testing of Legionella spp.Etest在嗜肺军团菌属抗菌药物敏感性试验中的应用
Diagn Microbiol Infect Dis. 1994 Jul;19(3):175-8. doi: 10.1016/0732-8893(94)90063-9.
8
In vitro activity of gatifloxacin, compared with ciprofloxacin, clarithromycin, erythromycin, and rifampin, against Legionella species.加替沙星与环丙沙星、克拉霉素、红霉素和利福平相比，对军团菌属的体外活性。
Diagn Microbiol Infect Dis. 1999 Apr;33(4):261-5. doi: 10.1016/s0732-8893(98)00150-3.
9
Susceptibility of Legionella species to antimicrobial agents.军团菌属对抗菌药物的敏感性。
Pathology. 1993 Apr;25(2):180-3. doi: 10.3109/00313029309084795.
10
Susceptibility of Legionella spp. to imipenem and 27 other beta-lactam antibiotics.嗜肺军团菌对亚胺培南及其他27种β-内酰胺类抗生素的敏感性
Eur J Clin Microbiol. 1984 Oct;3(5):463-7. doi: 10.1007/BF02017376.
引用本文的文献
1
Description and validation of a spectrum score method to measure antimicrobial de-escalation in healthcare associated pneumonia from electronic medical records data.一种基于电子病历数据测量医疗相关肺炎抗菌药物降阶梯治疗的谱评分方法的描述与验证
BMC Infect Dis. 2015 Apr 25;15:197. doi: 10.1186/s12879-015-0933-9.
2
Mistaken identity: Legionella micdadei appearing as acid-fast bacilli on lung biopsy of a hematopoietic stem cell transplant patient.身份误认：米德戴军团菌在一名造血干细胞移植患者的肺活检中表现为抗酸杆菌。
Transpl Infect Dis. 2015 Feb;17(1):89-93. doi: 10.1111/tid.12334. Epub 2015 Jan 9.
3
Comparison of charcoal- and starch-based media for testing susceptibilities of Legionella species to macrolides, azalides, and fluoroquinolones.用于检测军团菌属对大环内酯类、氮杂内酯类和氟喹诺酮类药物敏感性的基于木炭和淀粉的培养基的比较。
J Clin Microbiol. 1997 Nov;35(11):3004-6. doi: 10.1128/jcm.35.11.3004-3006.1997.
4
Azithromycin inhibition of intracellular Legionella micdadei.阿奇霉素对胞内米克戴德军团菌的抑制作用。
Antimicrob Agents Chemother. 1993 Nov;37(11):2261-4. doi: 10.1128/AAC.37.11.2261.
5
Susceptibility of Legionella spp. to mycinamicin I and II and other macrolide antibiotics: effects of media composition and origin of organisms.嗜肺军团菌对麦迪霉素 I 和 II 及其他大环内酯类抗生素的敏感性：培养基成分和菌株来源的影响
Antimicrob Agents Chemother. 1982 Jul;22(1):90-3. doi: 10.1128/AAC.22.1.90.
6
Characterization of the beta-lactamases of six species of Legionella.六种军团菌β-内酰胺酶的特性分析
J Bacteriol. 1982 Jul;151(1):216-21. doi: 10.1128/jb.151.1.216-221.1982.
7
Bactericidal activity of antibiotics against Legionella micdadei (Pittsburgh pneumonia agent).抗生素对米克戴德军团菌（匹兹堡肺炎病原体）的杀菌活性。
Antimicrob Agents Chemother. 1982 Aug;22(2):272-6. doi: 10.1128/AAC.22.2.272.
8
In vitro comparison of the activity of RU 28965, a new macrolide, with that of erythromycin against aerobic and anaerobic bacteria.新型大环内酯类药物RU 28965与红霉素对需氧菌和厌氧菌活性的体外比较。
Antimicrob Agents Chemother. 1984 Apr;25(4):529-31. doi: 10.1128/AAC.25.4.529.
9
Susceptibility of Legionella spp. to imipenem and 27 other beta-lactam antibiotics.嗜肺军团菌对亚胺培南及其他27种β-内酰胺类抗生素的敏感性
Eur J Clin Microbiol. 1984 Oct;3(5):463-7. doi: 10.1007/BF02017376.
10
Disk diffusion antimicrobial susceptibility testing of members of the family Legionellaceae including erythromycin-resistant variants of Legionella micdadei.军团菌科成员的纸片扩散法抗菌药物敏感性试验，包括米克戴德军团菌的耐红霉素变异株。
J Clin Microbiol. 1984 Jun;19(6):723-9. doi: 10.1128/jcm.19.6.723-729.1984.
本文引用的文献
1
Antimicrobial susceptibility of Legionella pneumophila Serogroups I--IV.
Scand J Infect Dis. 1980;12(3):215-9. doi: 10.3109/inf.1980.12.issue-3.09.
2
Susceptibility of Legionella pneumophila to twenty antimicrobial agents.嗜肺军团菌对二十种抗菌药物的敏感性
Antimicrob Agents Chemother. 1980 Sep;18(3):403-8. doi: 10.1128/AAC.18.3.403.
3
Pittsburgh pneumonia agent: direct isolation from human lung tissue.匹兹堡肺炎病原体：直接从人肺组织中分离得到。
J Infect Dis. 1980 Jun;141(6):727-32. doi: 10.1093/infdis/141.6.727.
4
Legionella gormanii sp. nov.戈尔曼军团菌新种
J Clin Microbiol. 1980 Nov;12(5):718-21. doi: 10.1128/jcm.12.5.718-721.1980.
5
Legionella micdadei (Pittsburgh pneumonia agent): direct fluoresent-antibody examination of infected human lung tissue and characterization of clinical isolates.麦氏军团菌（匹兹堡肺炎病原体）：对受感染的人肺组织进行直接荧光抗体检测及临床分离株的特性研究
J Clin Microbiol. 1981 Apr;13(4):720-2. doi: 10.1128/jcm.13.4.720-722.1981.
6
TATLOCK bacterium (Pittsburgh pneumonia agent) presumptively identified in five cases of pneumonia.
Ann Intern Med. 1980 Apr;92(4):510. doi: 10.7326/0003-4819-92-4-510.
7
Laboratory diagnosis of Legionnaires' disease.军团病的实验室诊断
Am Rev Respir Dis. 1980 Feb;121(2):317-27. doi: 10.1164/arrd.1980.121.2.317.
8
"Pittsburgh pneumonia agent": a bacterium phenotypically similar to Legionella pneumophila and identical to the TATLOCK bacterium.“匹兹堡肺炎病原体”：一种在表型上与嗜肺军团菌相似且与塔特洛克菌相同的细菌。
Ann Intern Med. 1980 Jan;92(1):53-4. doi: 10.7326/0003-4819-92-1-53.
9
The rickettsia-like organisms TATLOCK (1943) and HEBA (1959): bacteria phenotypically similar to but genetically distinct from Legionella pneumophila and the WIGA bacterium.立克次氏体样生物TATLOCK（1943年）和HEBA（1959年）：表型与嗜肺军团菌和WIGA细菌相似但基因不同的细菌。
Ann Intern Med. 1980 Jan;92(1):45-52. doi: 10.7326/0003-4819-92-1-45.
10
Laboratory evaluation of a rapid, automatic susceptibility testing system: report of a collaborative study.一种快速自动药敏试验系统的实验室评估：一项合作研究报告
Antimicrob Agents Chemother. 1975 Apr;7(4):466-80. doi: 10.1128/AAC.7.4.466.
Zotero 插件