Hamberger B, Bengtsson L, Järnberg P O, Farnebo L O
Acta Chir Scand Suppl. 1984;520:109-13.
The sympatho-adrenal activity as reflected in plasma catecholamine levels was studied in rats subjected to a standardized hemorrhage. A comparison was performed between awake rats and rats anesthetized with diethylether, enflurane, barbiturate or ketamine. As expected diethylether increased sympathoadrenal activity. Enflurane induction increased adrenaline and decreased noradrenaline levels. Upon hemorrhage the sympatho-adrenal activity was depressed compared to the awake state. Barbiturate anesthesia depressed sympatho-adrenal activity. Ketamine increased noradrenaline levels and a relative hypertension was noticed during bleeding. The results focus attention on important differences in sympatho-adrenal activity between awake rats and rats anesthetized with different agents.
在经历标准化出血的大鼠中，研究了血浆儿茶酚胺水平所反映的交感 - 肾上腺活动。对清醒大鼠与用乙醚、恩氟烷、巴比妥酸盐或氯胺酮麻醉的大鼠进行了比较。正如预期的那样，乙醚增加了交感 - 肾上腺活动。恩氟烷诱导增加了肾上腺素水平并降低了去甲肾上腺素水平。出血时，与清醒状态相比，交感 - 肾上腺活动受到抑制。巴比妥酸盐麻醉抑制了交感 - 肾上腺活动。氯胺酮增加了去甲肾上腺素水平，并且在出血期间观察到相对高血压。结果将注意力集中在清醒大鼠与用不同药物麻醉的大鼠之间交感 - 肾上腺活动的重要差异上。
