香豆素衍生物对人体免疫系统的影响。
The effect of coumarin derivatives on the immunological system of man.
作者信息
Berkarda B, Bouffard-Eyüboğlu H, Derman U
出版信息
Agents Actions. 1983 Feb;13(1):50-2. doi: 10.1007/BF01994281.
PMID:6602468
Abstract
Peripheral blood lymphocyte mitogen responsiveness was studied in 12 normal and 51 cancer patients. One group of patients was treated with warfarin, the second group with coumarin. There was a significant increase in lymphocyte response to phytohaemagglutinin (PHA) following both drugs. This increase indicates that both agents are capable of activating lymphocytes and thus stimulating some immunological functions.
摘要
对12名正常人和51名癌症患者的外周血淋巴细胞促有丝分裂原反应性进行了研究。一组患者接受华法林治疗，第二组接受香豆素治疗。两种药物治疗后，淋巴细胞对植物血凝素（PHA）的反应均显著增加。这种增加表明这两种药物都能够激活淋巴细胞，从而刺激一些免疫功能。
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