在检测耐青霉素的草绿色链球菌时，传代培养时尽量减少残留效应的重要性。
Importance of minimizing carry-over effect at subculture in the detection of penicillin-tolerant viridans group streptococci.
作者信息
Dankert J, Holloway Y, Joldersma W, Hess J
出版信息
Antimicrob Agents Chemother. 1983 Apr;23(4):614-6. doi: 10.1128/AAC.23.4.614.
Abstract
Penicillin susceptibility determinations made for 14 strains of Streptococcus mitior by two different broth dilution tests revealed small numbers of tolerant strains regardless of the volumes (0.01 and 0.1 ml) of subcultured broth. The addition of penicillinase to the subculture medium increased the number of tolerant strains significantly in 0.1 ml of subcultured broth, demonstrating that the detection of penicillin-tolerant viridans group streptococci might be hampered by the carry-over of penicillin.
摘要
通过两种不同的肉汤稀释试验对14株轻链球菌进行青霉素敏感性测定，结果显示，无论传代培养肉汤的体积（0.01和0.1毫升）如何，耐受菌株的数量都很少。在传代培养基中添加青霉素酶显著增加了0.1毫升传代培养肉汤中耐受菌株的数量，这表明青霉素的残留可能会妨碍对耐青霉素的草绿色链球菌的检测。
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