一个HLA - DR5纯合细胞系表达两种DS（I - A样）分子。
An HLA-DR5 homozygous cell line expresses two DS (I-A-like) molecules.
作者信息
Karr R W, Kannapell C C, Zangara R J, Goyert S M, Silver J, Schwartz B D
出版信息
J Exp Med. 1983 Oct 1;158(4):1374-9. doi: 10.1084/jem.158.4.1374.
Abstract
Previous studies have indicated that LLA-DR homozygous cell lines express two DR molecules but only a single DS (I-A-like) molecule. This report demonstrates that an HLA-DR5 homozygous cell line expresses at least two distinct DS molecules. These two DS molecules are formed by the association of a single DS alpha chain with either of two DS beta chains. Four distinct Ia molecules have now been identified from this DR5 homozygous cell line.
摘要
先前的研究表明，LLA-DR纯合细胞系表达两种DR分子，但仅表达一种单一的DS（I-A样）分子。本报告证明，一种HLA-DR5纯合细胞系至少表达两种不同的DS分子。这两种DS分子是由单一的DSα链与两种DSβ链中的任意一种结合形成的。现已从该DR5纯合细胞系中鉴定出四种不同的Ia分子。
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