人类B细胞同种异体抗原DC1、MT1和LB12彼此相同，但与HLA - DR抗原不同。
Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen.
作者信息
Shackelford D A, Mann D L, van Rood J J, Ferrara G B, Strominger J L
出版信息
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4566-70. doi: 10.1073/pnas.78.7.4566.
Some human B-lymphoblastoid cell lines are shown to express at least two types of Ia-like antigens. One antigen is defined by alloantisera to HLA-DR, and the other antigen is defined by alloantisera and a monoclonal antibody to the specificities DC1, MT1 (MB1), and LB12, which are in linkage disequilibrium with HLA-DR. The subunits of the DC1 molecule differ from those of the DR molecule. The light chains of both molecules are structurally polymorphic.
一些人B淋巴母细胞系显示至少表达两种类型的Ia样抗原。一种抗原由针对HLA-DR的同种抗血清所界定，另一种抗原由针对与HLA-DR处于连锁不平衡状态的特异性DC1、MT1（MB1）和LB12的同种抗血清及单克隆抗体所界定。DC1分子的亚基与DR分子的亚基不同。这两种分子的轻链在结构上具有多态性。
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