C反应蛋白与系统性红斑狼疮疾病活动的血清学指标
C-reactive protein and serological indices of disease activity in systemic lupus erythematosus.
作者信息
Bertouch J V, Roberts-Thompson P J, Feng P H, Bradley J
出版信息
Ann Rheum Dis. 1983 Dec;42(6):655-8. doi: 10.1136/ard.42.6.655.
Abstract
The concentration of C-reactive protein (CRP) in sera from 70 patients with systemic lupus erythematosus (SLE) showed no correlation with commonly accepted laboratory indices of disease activity. Most patients had detectable serum CRP, but in some patients CRP was not found despite repeated testing. This absence of a CRP response did not appear to be related to medication. In some patients high levels of CRP were seen in the absence of infection. Measurement of serum CRP in SLE is unlikely to be useful in the laboratory diagnosis of disease activity.
摘要
70例系统性红斑狼疮（SLE）患者血清中C反应蛋白（CRP）的浓度与公认的疾病活动实验室指标无相关性。大多数患者血清CRP可检测到，但部分患者尽管反复检测仍未发现CRP。CRP反应缺失似乎与用药无关。部分患者在无感染情况下出现高CRP水平。测定SLE患者血清CRP对疾病活动的实验室诊断可能并无帮助。
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