Khan M A
Br J Rheumatol. 1983 Nov;22(4 Suppl 2):129-33. doi: 10.1093/rheumatology/xxii.suppl_2.129.
The distribution of HLA alleles in B27 negative AS and Reiter's syndrome patients is reviewed. Some groups have reported an increased incidence of B7-CREG antigens (B7, B22 and B40) in B27 negative Caucasian AS patients, but we could not confirm these results, although an increased incidence of B7 was found in our B27 negative American Black patients with AS. Studies with larger numbers of B27 negative AS patients of various racial groups are needed to establish clearly if there is an association with B7-CREG antigens.
本文综述了B27阴性强直性脊柱炎（AS）和赖特综合征患者中HLA等位基因的分布情况。一些研究小组报告称，在B27阴性的白种人AS患者中，B7-CREG抗原（B7、B22和B40）的发生率有所增加，但我们无法证实这些结果，尽管在我们研究的B27阴性美国黑人AS患者中发现B7的发生率有所增加。需要对更多不同种族的B27阴性AS患者进行研究，以明确是否与B7-CREG抗原存在关联。
