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Enteric bacteria and HLA-B27 associated cell surface modification in patients with seronegative spondarthritis.

作者信息

Edmonds J, Geczy A F, Sullivan J S, Prendergast J K, Upfold L I, Bashir H V

出版信息

Br J Rheumatol. 1983 Nov;22(4 Suppl 2):75-82. doi: 10.1093/rheumatology/xxii.suppl_2.75.

DOI:10.1093/rheumatology/xxii.suppl_2.75
PMID:6606476
Abstract

Cytotoxic studies indicate cross-reactivity between some enteric organisms and cells obtained from the majority of patients with ankylosing spondylitis. Preliminary studies suggest that the factor responsible for cross-reactivity may be generated by a bacterial plasmid. However, the mechanism mediating the interaction between the HLA-B27 positive cell and the bacterial antigen is at present unknown.

摘要

相似文献

1
Enteric bacteria and HLA-B27 associated cell surface modification in patients with seronegative spondarthritis.
Br J Rheumatol. 1983 Nov;22(4 Suppl 2):75-82. doi: 10.1093/rheumatology/xxii.suppl_2.75.
2
A reinvestigation of the cross-reactivity between Klebsiella and HLA-B27 in the aetiology of ankylosing spondylitis.对克雷伯菌与人类白细胞抗原B27在强直性脊柱炎病因学中的交叉反应性的重新研究。
Clin Exp Immunol. 1985 Dec;62(3):662-71.
3
Significance of non-pathogenic cross reactive bowel flora in patients with ankylosing spondylitis.非致病性交叉反应性肠道菌群在强直性脊柱炎患者中的意义。
Ann Rheum Dis. 1986 Jul;45(7):566-71. doi: 10.1136/ard.45.7.566.
4
HLA-B27 associated cross-reactive marker on the cells of New Zealand patients with ankylosing spondylitis.新西兰强直性脊柱炎患者细胞上的HLA - B27相关交叉反应标志物。
Ann Rheum Dis. 1986 Feb;45(2):144-8. doi: 10.1136/ard.45.2.144.
5
The role of Klebsiella in the pathogenesis of ankylosing spondylitis. II Evidence for a specific B27-associated marker on the lymphocytes of patients with ankylosing spondylitis.克雷伯氏菌在强直性脊柱炎发病机制中的作用。II. 强直性脊柱炎患者淋巴细胞上特定B27相关标志物的证据。
J Clin Lab Immunol. 1980 Jan;3(1):23-8.
6
Possible role of enteric organisms in the pathogenesis of ankylosing spondylitis and other seronegative arthropathies.肠道微生物在强直性脊柱炎和其他血清阴性关节病发病机制中的可能作用。
Infect Immun. 1983 Sep;41(3):935-41. doi: 10.1128/iai.41.3.935-941.1983.
7
Is a Klebsiella plasmid involved in the aetiology of Ankylosing Spondylitis in HLA-B27-positive individuals?
Mol Immunol. 1983 May;20(5):563-6. doi: 10.1016/0161-5890(83)90095-0.
8
Cross-reactivity of anti-Klebsiella K43 antiserum and lymphocytes from HLA-B27-positive patients with ankylosing spondylitis.
Lancet. 1985 Mar 30;1(8431):764. doi: 10.1016/s0140-6736(85)91313-3.
9
An antiserum to a disease-associated factor from the cells of an HLA-B27 positive patient with ankylosing spondylitis specifically recognizes an HLA-B27 associated determinant.来自一名患有强直性脊柱炎的 HLA - B27 阳性患者细胞的疾病相关因子的抗血清特异性识别一种 HLA - B27 相关决定簇。
Arthritis Rheum. 1987 Apr;30(4):439-42. doi: 10.1002/art.1780300412.
10
Ankylosing spondylitis, HLA-B27 and Klebsiella. I. Cross-reactivity studies with rabbit antisera.强直性脊柱炎、HLA - B27与克雷伯菌。I. 用兔抗血清进行的交叉反应研究。
Br J Exp Pathol. 1980 Feb;61(1):85-91.

引用本文的文献

1
The modification of HLA-B27-positive lymphocytes by the culture filtrate of Klebsiella K43 BTS 1 is a metabolically active process.肺炎克雷伯菌K43 BTS 1的培养滤液对HLA - B27阳性淋巴细胞的修饰是一个代谢活跃的过程。
Clin Exp Immunol. 1985 Dec;62(3):672-7.
2
Significance of non-pathogenic cross reactive bowel flora in patients with ankylosing spondylitis.非致病性交叉反应性肠道菌群在强直性脊柱炎患者中的意义。
Ann Rheum Dis. 1986 Jul;45(7):566-71. doi: 10.1136/ard.45.7.566.
3
Ankylosing spondylitis, HLA-B27, and Klebsiella: a study of lymphocyte reactivity of anti-Klebsiella sera.
强直性脊柱炎、HLA - B27与克雷伯菌：抗克雷伯菌血清淋巴细胞反应性研究
Ann Rheum Dis. 1986 Mar;45(3):190-7. doi: 10.1136/ard.45.3.190.
4
HLA-B27 associated cross-reactive marker on the cells of New Zealand patients with ankylosing spondylitis.新西兰强直性脊柱炎患者细胞上的HLA - B27相关交叉反应标志物。
Ann Rheum Dis. 1986 Feb;45(2):144-8. doi: 10.1136/ard.45.2.144.
5
Intestinal permeability, non-steroidal anti-inflammatory drug enteropathy and inflammatory bowel disease: an overview.肠道通透性、非甾体抗炎药肠病与炎症性肠病：综述
Gut. 1989 Nov;30 Spec No(Spec No):22-8. doi: 10.1136/gut.30.spec_no.22.
6
Klebsiella 'modifying factor': binding studies with HLA-B27+ and B27- lymphocytes.克雷伯菌“修饰因子”：与HLA - B27阳性和阴性淋巴细胞的结合研究
Ann Rheum Dis. 1985 Mar;44(3):169-75. doi: 10.1136/ard.44.3.169.
7
Polyclonal B cell activation in ankylosing spondylitis.强直性脊柱炎中的多克隆B细胞激活
Ann Rheum Dis. 1990 Jun;49(6):396-9. doi: 10.1136/ard.49.6.396.