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Staphylococcal protein-A is a potent T-cell mitogen of tonsillar lymphocytes.

作者信息

Jacob M C, Rose M L

出版信息

Immunol Lett. 1983;7(2):77-80. doi: 10.1016/0165-2478(83)90037-8.

DOI:10.1016/0165-2478(83)90037-8
PMID:6606618
Abstract

Optimal conditions for the stimulation of human tonsillar lymphocytes by staphylococcal protein-A (SpA) are described. By stimulating fractions enriched or depleted of E-rosette forming cells, the response was shown to be predominantly a T-cell response. A comparison of stimulation by SpA with that of phytohaemagglutinin (PHA) proved SpA to be a potent T-cell mitogen. We suggest that SpA may be another useful mitogen for studying human T-cell growth and differentiation.

摘要

相似文献

1
Staphylococcal protein-A is a potent T-cell mitogen of tonsillar lymphocytes.
Immunol Lett. 1983;7(2):77-80. doi: 10.1016/0165-2478(83)90037-8.
2
Cellular cooperation in lymphocyte activation. I. Cooperative and noncooperative responses of human T and B lymphocytes to various mitogens.淋巴细胞激活中的细胞合作。I. 人T淋巴细胞和B淋巴细胞对各种有丝分裂原的协同和非协同反应。
Int Arch Allergy Appl Immunol. 1979;58(3):260-73.
3
Polyclonal activation of human lymphocytes in vitro. I. Characterization of the lymphocyte response to a T cell-independent B cell mitogen.人淋巴细胞在体外的多克隆激活。I. 淋巴细胞对T细胞非依赖性B细胞有丝分裂原反应的特征
J Immunol. 1980 Aug;125(2):820-6.
4
Immunological marker analysis of mitogen-induced proliferating lymphocytes using BrdU incorporation or screening of metaphases. Staphylococcal protein A is a potent mitogen for CD4+ lymphocytes.使用溴脱氧尿苷掺入法或中期筛选对丝裂原诱导的增殖淋巴细胞进行免疫标记分析。葡萄球菌蛋白A是CD4 +淋巴细胞的有效丝裂原。
Scand J Immunol. 1990 Dec;32(6):687-94. doi: 10.1111/j.1365-3083.1990.tb03211.x.
5
Activation of human T lymphocytes by soluble protein A.可溶性蛋白A对人T淋巴细胞的激活作用。
Scand J Immunol. 1985 Dec;22(6):603-10. doi: 10.1111/j.1365-3083.1985.tb01922.x.
6
Separation of mitogen-induced suppressor cells of human antibody-producing cells.人抗体产生细胞的丝裂原诱导抑制细胞的分离。
Cell Immunol. 1980 Sep 1;54(2):373-81. doi: 10.1016/0008-8749(80)90217-8.
7
Different mitogenic activity of soluble and insoluble staphylococcal protein A (SPA).可溶性和不溶性葡萄球菌蛋白A(SPA)的不同促有丝分裂活性。
Immunology. 1978 Sep;35(3):471-8.
8
Altered regulation of mitogen responsiveness by suppressor cells in multiple sclerosis.多发性硬化症中抑制细胞对有丝分裂原反应性的调节异常。
Clin Exp Immunol. 1979 Apr;36(1):78-84.
9
[Mitogen response of tonsillar lymphocytes to stimulation with phytohemagglutinins].
Srp Arh Celok Lek. 1986 Jan;114(1):9-17.
10
Detection of IL-2 receptor positive tonsillar lymphocytes by monoclonal antibody and protein A coated erythrocytes.用单克隆抗体和蛋白A包被的红细胞检测白细胞介素-2受体阳性的扁桃体淋巴细胞。
Immunol Lett. 1988 Jan;17(1):35-9. doi: 10.1016/0165-2478(88)90098-3.

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