非挥发性脂肪酸在非特异性阴道炎诊断中的应用
Non-volatile fatty acids in the diagnosis of non-specific vaginitis.
作者信息
Ison C A, Easmon C S, Dawson S G, Southerton G, Harris J W
出版信息
J Clin Pathol. 1983 Dec;36(12):1367-70. doi: 10.1136/jcp.36.12.1367.
Abstract
In the vaginal washings of 100 women with symptomatic non-specific vaginitis a succinate/lactate ratio of greater than or equal to 0.4 had a diagnostic sensitivity of 80%, a specificity of 83% for this condition. The predictive value of a positive test was 94%, but that of a negative test was only 55%. A strong association between the presence of Gardnerella vaginalis, anaerobes, a vaginal pH of above 4.5, and amines was found not only in non-specific vaginitis, but also in trichomonal and gonococcal infection. A variety of primary changes may encourage the multiplication of both gardnerellae and anaerobes and their presence in non-specific vaginitis may be a secondary rather than a primary event.
摘要
在100例有症状的非特异性阴道炎女性的阴道冲洗液中，琥珀酸盐/乳酸盐比值大于或等于0.4对该病症的诊断敏感性为80%，特异性为83%。阳性检测的预测值为94%，但阴性检测的预测值仅为55%。不仅在非特异性阴道炎中，而且在滴虫和淋球菌感染中，都发现阴道加德纳菌、厌氧菌的存在、阴道pH值高于4.5与胺之间存在密切关联。多种原发性改变可能会促使加德纳菌和厌氧菌繁殖，它们在非特异性阴道炎中的存在可能是继发性而非原发性事件。
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